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While not absolutely required for safety, cycling is recommended to prevent potential receptor desensitization and to allow for assessment of sustained effects

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Levels naturally decline with age, which has fuelled interest in whether supplementation can reverse age-related tissue changes

B12 is essential for healthy nerve cells and the production of myelin, the protective covering for nerves

Surface biotinylation assay To evaluate the surface expression of mutant receptors we carried out surface biotinylation assay

Open public hearing sessions are scheduled throughout both days