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After treating 3T3-L1 cells with GLP-1, some scholars found that the number of small and medium-sized adipocytes increased

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[42] pooled 31 long-duration RCTs (84,713 participants) of GLP-1 RAs in diabetes and obesity, populations again largely free of significant psychiatric comorbidity, and found no increase in depression, anxiety, or suicidality, providing robust evidence for psychiatric safety in large, controlled settings