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Our model suggests that the large male-female differences in GSH concentration and the velocity of its synthesis cause females to be less sensitive to APAP toxicity compared to males

Carbon Tetrachloride Liver Fibrosis Model The CCl (carbon tetrachloride) rodent model is the standard experimental liver fibrosis system: i.p

Conjugation It binds to toxins, forming conjugates that are more easily eliminated from the body, aiding in detoxification

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All molecular manipulations were carried out using standard cloning techniques ( L

Quantifying Escherichia coli glutaredoxin-3 substrate specificity using ligand-induced stability