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generated a novel family of non-covalent, benzimidazole-based DPP-4 inhibitors from a small fragment hit (110)

[DOI] [PMC free article] [PubMed] [Google Scholar] 141.Fiorucci S., Marchian S., Distrutti E., Biagioli M

10.1146/annurev-nutr-071816-064732 88

Additional file 1: Fig S4)

Unione Europea, agosto 2025), con un meccanismo dazione completamente diverso: un agonista del recettore beta degli ormoni tiroidei che agisce direttamente sul fegato, indipendentemente dalla perdita di peso