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This section is current as of June 2026

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Ferrous iron (Fe 2+ ) catalyzes the Fenton reaction with hydrogen peroxide, generating hydroxyl radicals ( OH) that extract hydrogen atoms from bis-allylic carbons of polyunsaturated fatty acids (PUFAs)

Besides being a potent antioxidant, NAC is also historically used to dissolve thick mucus in lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease (COPD)

Pasello et al reported that this agent effectively reversed cisplatin resistance in osteosarcoma, alluding toward potentially improved clinical outcomes when using a combination of NBDHEX and cisplatin