Additionally, both medications can affect fluid balance and renal perfusion, so baseline kidney function and electrolyte status should be assessed before initiating either therapy
Over time, it causes fewer dark spots, melasma, and hyperpigmentation, resulting in a lighter, more even-looking skin tone
New England Journal of Medicine 393 (11)
"The reduction in blood glucose and weight with Orforglipron is similar, if not a little bit better, than the similar clinical trials that were done for Ozempic and Mounjaro." The results of the trials, involving 500 adults with type 2 diabetes, were unveiled at the American Diabetes Association annual meeting in Chicago over the weekend
The other gets a denial letter and a suggestion to try diet and exercise first
Impact of GLP-1 on Glucagon Secretion GLP-1-induced inhibition of glucagon secretion has been demonstrated in a variety of species including humans (175, 195)