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IL-22 may also strengthen the gut barrier, reducing translocation of microbial products that exacerbate liver inflammation [73,74]

Platelets are activated during inflammation to release bioactive factors that exert pro-inflammatory and anti-inflammatory effects

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Although the regulatory bodies did not confirm these performance-enhancing effects, the use of TB-500 was quickly prohibited in the sport [12, 13]

doi: 10.1016/j.clnesp.2022.04.019 246 ArreolaRQuintero-FabinSLpez-RoaRIFlores-GutirrezEOReyes-GrajedaJPCarrera-QuintanarLet al