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Shu L, Matveyenko AV, Kerr-Conte J, Cho JH, McIntosh CH, Maedler K

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Researchers study Orforglipron to evaluate GLP-1 receptor activation, receptor signaling behavior, small-molecule agonist design, and oral GLP-1 pathway models under controlled laboratory conditions

Abbreviations RGCs: retinal ganglion cells GFAP: glial fibrillary acidic protein NOS: nitric oxide synthase NO: nitric oxide iNOS: inducible NOS MTC: methylcellulose Ub: ubiquitin MDA: malondialdehyde IOP: intraocular pressure References Cedrone C, Mancino R, Cerulli A, Cesareo M, Nucci C