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Never freeze a reconstituted vial, as that can ruin it

Trials have typically used titration periods of about 6 weeks, starting at a lower dose and stepping up to the full maintenance dose

People with serious vitamin B12 deficiency can result in anemia, stomach problems and nerve damage

Most patients notice initial improvements in sleep quality and recovery within 2 to 4 weeks

Do not eat or drink for 30 minutes

We also considered whether hospitals could encode a range of allowed amounts, as opposed to the exact count of allowed amounts, to achieve our objective of providing needed context to the allowed amount data element values