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As a sensitive indicator, any variation of the optimal intracellular ratios of GSH to GSSG can result in human diseases such as cancer, cardiac disease, apoplexy and many neurological disorders 10,11,12,13,14,15

Egras AM, Hamilton WR, Lenz TL, Monaghan MS

10.1074/jbc.M513737200 J

Spontaneous oxygen radical generation by sickle erythrocytes