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Depletion of GSH levels necessary for adequate protection to less than 20-30% has been suggested as an explanation of hepatotoxicity of higher doses of compounds such as paracetamol or bromobenzene [13]

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Thermo Fisher Scientific, Inc.) for 30 min at 37C, followed by incubation in the dark with Rhodamine 123 working solution (2 M

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Upon ligand binding, the receptor undergoes a conformational change that activates intracellular signalling pathways, primarily through the cyclic adenosine monophosphate (cAMP) second messenger system

Moreover, a GLP-1 analog, (Val(8))GLP-1-Glu-PAL, increased hippocampal neurogenesis and cell proliferation in obese mice fed a high-fat diet (Lennox et al., 2013)