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This disorder is associated with other chronic diseases, such as hypertension, stroke, depression, anxiety, and cardiovascular diseases (2, 5, 6)

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Glial cells, particularly microglia, are key contributors to neuroinflammation, with microglial activation leading to the production of proinflammatory cytokines like NO, IL-1, and TNF- 42

Targeting GSH synthesis/utilization therefore represents a potential means of rendering tumor cells more susceptible to different treatment options such as chemotherapy and radiotherapy

The density of PMNLs was estimated according to defined by Kara and colleagues.13 Biochemical analysis Lateral nasal wall mucosa samples sized 0.5cm2 were used for biochemical analysis