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Lactylation of histones or non-histone proteins involved in iron autophagy-related pathways can modulate iron handling, thereby regulating ferroptosis (70-72)

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The method is validated computationally against physiological temperature simulations for fast-diffusing compounds, as well as experimentally by direct determination of the compound permeabilities using a transwell assay as an in vitro BBB model

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found that resveratrol exerts renoprotective effects via its radical scavenging and antioxidant activities, which appear to involve the inhibition of tissue neutrophil infiltration (Felix et al., 2024)