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Phase I trials have been completed for hematological tumors (NCT02071888) and leukemias (NCT02071927), although no clinical data is publicized

The rs6265 variant is analyzed in the PlexusDx Precision Peptide Genetic Test as part of the Cognition pathway

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Statements Author contributions XZ: Data curation, Investigation, Methodology, Writing original draft, Writing review & editing

The interest in GLP-1 RAs for depression stems from several factors, including their consistent effect on weight reduction through appetite suppression and delayed gastric emptying, which may counteract antidepressant-related weight gain [176]