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A 2023 Phase 2 clinical study on retatrutide published in the New England Journal of Medicine demonstrated significant reductions in body weight in research participants, underscoring its importance as a research compound

Starting body composition plays a major role, with individuals carrying higher body fat percentages often experiencing more dramatic absolute changes, while leaner individuals may see slower but steady improvements in stubborn fat areas

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Routine Check-ups: Regular blood tests to monitor B12 levels