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The available animal studies were not sufficient to resolve this concern because they did not provide a comprehensive dose-ranging, long-term carcinogenicity programme

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Nrf2 Activation as a Strategy for COVID-19 Treatment The involvement of Nrf2 signalling in coronavirus disease 19 (COVID-19) is sustained by the marked cytoprotective ability of Nrf-2 in responding to stressors and its potential role in the treatment of pathologies characterized by oxidative and/or inflammatory events

D., Tasic, B., Miyamichi, K., Li, L

Experimental studies have demonstrated that tulsi helps reduce the effects of acute and chronic noise-induced stress in experimental animals, with enhancement of neurotransmitter and oxidative stress levels in discrete brain regions along with improved immune, ECG, and corticosteroid responses 28 29