Together, these B vitamins work synergistically to support energy levels, metabolism, mental clarity, and overall wellbeing
NNMT normally methylates nicotinamide using S-adenosylmethionine (SAM) as a methyl donor, producing 1-methylnicotinamide and S-adenosylhomocysteine
By reducing NNMT, the bodys ability to burn fat doesnt slow down and fat cells dont continue growing
B12 supplementation is one of the most common additions, addressing the potential for micronutrient deficiency when caloric intake drops significantly
Studies suggest it may activate satellite cells in muscle tissue, potentially improving contractile force and muscle density even during a caloric deficit
Inclusion criteria were: (a) RCTs