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To demonstrate the advantages of bivalent target binding through the full IgG format for enhancing avidity and selectivity, compared to most clinically approved bispecific T cell engagers that rely on monovalent binding, we introduced mutations (H91A and Y92A) in the complementarity-determining regions of Her2 to generate Her2 variants with reduced target binding affinity

Barst, R

Q9: Will the tablet change colour over time

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Parry-Strong A, Langdana F, Haeusler S, Weatherall M, Krebs J

Post-procedure tips: Results start appearing within 34 months and mature completely in 1012 months