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145 Under oxidative stress, Cys34 thiol shifts to a sulfenic acid (HSA-SOH), which can be irreversibly oxidized to the sulfinic (HSA-SO2H) and sulfonic (HSA-SO3H) acids or, through the reactions with glutathione, can be returned to the HSA-SH reduced form

However, various toxic influences shift the balance in the body toward the oxidized state

The patients were administered vitamin C and Pinus bark in the aforementioned doses for 3 months

Important Limitations of Use : [1] Not recommended as first-line therapy for patients inadequately controlled on diet and exercise

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Carnosine and homocarnosine, the forgotten, enigmatic peptides of the brain