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The FDA evaluated the above claim and found that while it is known that diets low in saturated fat and cholesterol reduce the risk of heart disease and other vascular diseases, the evidence in support of the above claim is inconclusive

High-throughput analysis reveals miRNA upregulating alpha-2,6-sialic acid through direct miRNA-mRNA interactions

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Preclinical Research: Fat Metabolism and Adiposity Initial animal studies conducted in the early 2000s reported that chronic exposure to AOD-9604 in obese mice and Zucker rats led to reductions in weight gain and increased fat oxidation

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J Biol Chem (2000) 275(39):305204