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Discussion To our knowledge, this study represents the first human laboratory investigation of the effects of cannabis administration, via different routes (i.e., oral, smoked, and vaporized), on peripheral concentrations of appetitive and metabolic hormones in a sample of occasional and frequent cannabis users

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While the principles of antiseizure treatment are similar to those applied in younger adults, several age-specific considerations must be taken into account: Pharmacokinetics and tolerability: Age-related changes in hepatic and renal metabolism, altered protein binding, and increased drug sensitivity necessitate careful selection and dosing of antiseizure medications (ASMs)