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In contrast to the general belief, recent research in healthy tissue from animals suggests that LPS is not crossing the epithelium via the paracellular pathway (19)

L., Chu, J

Leaky Gut Syndrome A 34-year-old female with IBS symptoms and post-antibiotic dysbiosis completed a 90-day low-dose protocol (0.3mg daily), with notable improvement in bloating, bowel regularity, and gut-related fatigue

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Implementing periodic washout phasessuch as 5 days on, 2 days off, or alternating weekspreserves receptor sensitivity while maintaining neuroplastic stimulus across extended protocols

We therefore reason from mechanism and animal models rather than from human numbers