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Mesolimbic dopamine system Nodes of the mesolimbic reward circuitry are also impacted by local GLP-1r signaling

However, the structurally modified version of the tetra-substituted peptide, Modified GRF 1-29, is considered to boast a longer half-life and has, therefore, been considered by researchers as a more viable compound for use during experimental research

Two recent studies in the JCI provide insight into the neurons responsible for this effect