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Einother SJ, Martens VE, Rycroft JA, et al

What we do not have: large-scale human RCTs

Serum glutathione levels can fall by as much as 26% in pregnant women compared to non-pregnant women, with an 80% decrease between the first to second trimester [74,75]

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Genetic fate tracking with Esm1-CreERT2 transgenic mice has established that tip cell progeny contributes to the arterial but not the venous branch of the vasculature, which involves signaling interactions via the Notch pathway, the chemokine receptor CXCR4 and its ligand CXCL12, and interactions between ephrin-B2 and its receptor EphB4 11,12,13

10.1523/JNEUROSCI.3516-16.2017 J Neurosci