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That is why the documented practice is to dose on an empty stomach a common rule of thumb in the research framing is a fasted window before and after the injection, with no food or caloric drinks in that window

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The Office of Dietary Supplements of National Institutes of Health gives fact sheets about certain nutrients, including vitamin B12, in which they clarify that while generally considered safe, there are certain concerns regarding the dosage, form, and stability of the injectable version of vitamin B12 as compared to oral supplements