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These damaged T-cells produce markedly less protective cytokines like IFN- and TNF- when stimulated, leaving the patient vulnerable to opportunistic infections and viral reactivation

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The short answer is yes

An important nuance: about three-quarters of the weight lost was fat, while roughly one-quarter was lean mass (muscle, water, bone density)

But they are marketed and used for many other purposes, which could be permitted if the drugs were cleared

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