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En las personas con DM2 se observa una disminucin de este efecto fisiolgico y disminucin de la secrecin de GIP y, especialmente, de GLP-1, aunque este efecto parece ser reversible cuando se administra GLP-1 exgeno (pero no GIP), pudiendo revertir parcialmente la respuesta insulnica

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Recent meta-analyses and large-scale cohort studies have provided robust supporting evidence that MBS is more favourable than GLP-1 receptor agonists in reducing both MACE and all-cause mortality in individuals with obesity and type 2 diabetes

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Astilbin targeted Sirt1 to inhibit acetylation of Nrf2 to alleviate grass carp hepatocyte apoptosis caused by PCB126-induced mitochondrial kinetic and metabolism dysfunctions