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If this theory is true, the idea is that because the immune and nervous systems are so energetically demanding, the body will eventually deplete in the nutrients and co-factors required for proper energy production, which drives a lot of the classic symptoms like fatigue, brain fog, rapid heart rate and blood pressure changes, and exercise intolerance

This decline contributes to many age-related changes like decreased muscle mass, increased body fat, reduced bone density, and lower energy levels

& Bernardi, P

Both metformin and Ozempic have been shown to help with weight loss in addition to their primary function of lowering average blood sugar levels

Metastasis is the leading cause of cancer-related mortality (Zhang et al

How does this combination compare to GLP-1 agonists like semaglutide for metabolic health