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Concomitant use with metformin, sulfonylureas, dipeptidyl peptidase-4 (DPP-4) inhibitors, or insulin targets multiple pathways involved in glucose metabolism

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doi: 10.1016/0006-8993(90)91240-h 31 BouthenetMLRuatMSalesNGarbargMSchwartzJC

But we need more data on long-term safety, real-world effectiveness, and who benefits most

Nausea Is the Most Common Side Effect Nausea is the most frequently reported adverse effect