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However, sample sizes were modest, and long-term safety and efficacy data remain absent from peer-reviewed literature

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Fico A, Paglialunga F, Cigliano L, Abrescia P, Verde P, Martini G et al

Investigations are guided by clinical suspicion rather than routine panels: for example, thyroid function tests and ferritin may be checked if symptoms suggest deficiency or thyroid disease, while an androgen profile may be appropriate in women presenting with menstrual irregularity, hirsutism, or acne

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