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In my functional medicine practice, Ive identified several patient populations who may benefit from a microdosing approach: Individuals Seeking Modest Weight Loss Not everyone needs to lose 50 pounds

37 Obesity increases the risk of comorbidities like hypertension, DM2, hyperlipidemia, stroke, and some cancers, leading to higher mortality rates, primarily from cardiovascular complications

Dihydrofolate reductase (DHFR) controls the regeneration of BH2 to BH4, in which NAD(P)H is the principal cofactor that supplements BH4 but not BH2

HDAC2 mRNA and protein expression levels and HDAC2 activity were also analyzed

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