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doi: 10.1093/gerona/glaa185 74 AzzolinoDArosioBMarzettiECalvaniRCesariM

Semaglutide is meant to be titrated up gradually, with most individuals finding the 0.50mg-1.00mg dose to be the "sweet spot" for weight loss

Key Takeaways The C rating of a LiPo battery shows how fast it gives energy

Pickart estimated lethal dose at approximately 22,500 mg for humans (300-fold above effective doses), with animal LD50 studies in mice showing 8 mg per 25g mouse (320 mg/kg, translating to ~22,400 mg for 154 lb human)

Traditionally, these GLP-1 agonists have been used to treat diabetes and heart disease

2020;59(suppl 4):iv38-iv46