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doi:10.1210/jcem.83.6.4873 Astrup A, et al
Wnt5a activats Wnt/PCP pathway, upregulating Ras-related C3 botulinum toxin substrate 1(Rac), which can activate JNK, thus aggravating IR in adipose tissue
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The Wegovy prescribing information states that overdoses have been reported with other GLP-1 receptor agonists, with effects including severe nausea, severe vomiting and severe hypoglycemia, and that appropriate supportive treatment should be initiated according to the patients clinical signs and symptoms
