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TD Cowen analyst Steve Scala has flagged the high rate of discontinuation as a concern and suggested it could make outcomes of future trials harder to predict

Making it unclear if drinking green tea or yerba mate has a significant effect on GLP-1 levels in humans

Phase 2 dose-escalation data showed mean weight loss of 24.2% at 48 weeks at the highest dose tested substantially exceeding semaglutide's 14.9% and approaching tirzepatide's 22.5% in comparable timeframes

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At 8mg, it hit 81.4%

That's why it's important to include sources of B vitamins in your daily diet, such as legumes, green veggies, whole grains, eggs and meat