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Allergic reactions Allergy to vitamin B12 is quite uncommon, but some people might experience allergic symptoms, especially when they first start supplementing

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Some of the key benefits include: Boosted Energy & Reduced Fatigue When B12 is low, many people feel sluggish

[9] [2] According to NICE guidance, patients with confirmed B12 deficiency and neurological involvement typically require more frequent initial dosing (alternate-day injections) until symptom improvement occurs

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How Quickly Does a B12 Shot Work Many people feel the effects of a B12 shot within 24 to 72 hours, especially if they were deficient