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References Dukowicz AC, Lacy BE, Levine GM

The reduced form is the predominant one and GSSG is maintained at low levels, less than 1% mainly by the action of NADPH-dependent glutathione reductase [13], which converts GSSG into the reduced GSH (Figure 1)

3-Aminobenzamide-linked multifunctional nanoparticles enhances anticancer activity of low-dose cisplatin chemotherapy in lung adenocarcinoma

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The latest study by the same group suggests that this effect may result from Mn impairing lysosomal protein degradation (Rokad et al., 2024)