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The Keto-Flu A common adverse effect of the ketogenic diet is the keto-flu. The symptoms are indicative of carbohydrate withdrawal that can create symptoms like brain fog, fatigue, nausea, vomiting, constipation, and muscle soreness

doi: 10.1210/jc.2016-2300 45 EliaGFerrariSMGaldieroMRRagusaFPaparoSRRuffilliIet al

10.3390/ijms22083923 Int J Mol Sci

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While the precise mechanisms of zonulin's regulation are still under investigation, it is believed that zonulin interacts with specific receptors on the surface of epithelial cells, initiating intracellular signaling pathways that affect the tight junctions' integrity and permeability

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