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Our peer-reviewed JMIR study showed people on the semaglutide-supported programme lost an average of 19.1% of their body weight at 12 months, with 77.7% achieving at least 10% weight loss

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In contrast, they found a positive association between fasting levels of ghrelin and food reward responses in the amygdala, hippocampus, anterior insula, and OFC in healthy control participants (Holsen et al., 2014)