Consequently, Zubair et al did not recommend glutathione as a skin-lightening agent.14 In contrast, Weschawalit et al3 reported a statistically significant effect of glutathione as a skin-lightening agent, but this was limited to a group of participants aged older than 40 years who received GSH, a reduced form of glutathione, on the sun-exposed area of the right forearm.3 Arjinpathana et al1 used a Mexameter (Courage+Khazaka Electronic, Kln, Germany) to measure the melanin index as the main output parameter and found that glutathione was most effective on sun-exposed skin.1 In their systematic review, Dilokthornsakul et al15 likewise reported that glutathione might lighten skin tone in sun-exposed areas
Compounded drugs are custom made and not FDA approved
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P2-P5: se refieren al uso del doble ciego
Statistical analysis Statistical analyses were performed using Review Manager Software (Cochrane Collaboration, version 5.4.0)
Diluting protein powder with extra water or unsweetened almond milk creates a lighter beverage that may be easier to consume