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It is FDA-approved to improve glycemic control in adults with Type 2 diabetes and is also prescribed off-label for weight loss

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A randomized trial of high-dose (HD) imatinib mesylate (IM) with or without Peg-interferon (PEG-IFN) and GM-CSF as frontline therapy for patients with chronic myeloid leukemia (CML) in early chronic phase (CP)