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Dozens of wellness and direct-to-consumer telehealth companies offering GLP-1s have begun marketing cash-pay hormone replacement therapy to women in perimenopause and menopause, and testosterone replacement therapy to men

Currently, 1 in 20 US adults is taking GLP-1 drugs, and more than 1 in three are eligible

SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells

For Ozempic, which is FDA-approved for type 2 diabetes, the dosing schedule starts at 0.25 mg and escalates, with options to increase to 0.5 mg at week five, then 1.0 mg, and potentially up to 2.0 mg

For patients with baseline NAFLD (non-alcoholic fatty liver disease) or elevated transaminases, glutathione supplementation timed correctly can support hepatic antioxidant capacity during this metabolic surge

Deshwal, R., Iqbal, M