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Furthermore, peptides of soy protein, rice protein, and hydrolysate of wheat gliadin derived from wheat (Teschemacher, 2003) have opioid activity and can cause an increase in the antioxidant and methylation capacity of nerve cells (Trivedi et al., 2014) and lower the NO level across the cellular environment (Yin et al., 2015)

This ability may contribute to the prevention of atherosclerotic plaque development and its associated clinical complications [1,2,3]

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Thus, trigonelline might be an interesting therapeutic strategy as an NAD + modulator to explore in sarcopenia and possibly other chronic conditions

By addressing the root causes of cellular aging, Epitalon offers a promising strategy to not only extend lifespan but also enhance the quality of life as we age