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Nausea, vomiting, diarrhea, constipation, reflux, and reduced appetite can occur with incretin-based therapies

Emerging findings indicate that GLP-1 receptor agonists may influence neural and cognitive mechanisms underlying this phenomenon, including reward anticipation and cue reactivity, whereas mindfulness-based interventions appear to act on attentional regulation and aspects of DMN activity relevant to craving and rumination

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Hollander PA, Levy P, Fineman MS, et al