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However, treatment with rutin nanoformulation significantly reduced both the severity and extent of pathological changes in the colon

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Yen FS, Hsu CC, Wei JCC, Tsai FJ, Huang Y, Yu TS, et al

Toxicology & Safety Profiling: Assess offtarget sympathomimetic effects, renal and muscle toxicity risks, and doselimiting tolerability in animal studies PubMed