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Chemical Formula: HO (with 0.9% benzyl alcohol: CHO) Molecular Weight: 18.0 g/mol (water), 108.1 g/mol (benzyl alcohol) For research purposes only
Daughton CG, Ternes TA
Its status as a research-only chemical automatically places it on the prohibited list
10.1007/s00394-004-0448-4 44
In murine models of doxorubicin (DOX) and ischemia/reperfusion (I/R)-induced cardiomyopathy, administering DOX to mice induced cardiomyopathy with a rapid, systemic accumulation of non-heme iron via heme degradation by Nrf2-mediated upregulation of HO-1, which effect was abolished in Nrf2-deficient mice (van Raaij et al., 2018)
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