Knee osteoarthritis Semaglutide 47 and liraglutide 27 were assessed in patients with obesity and knee osteoarthritis (KOA)
Contact your provider if you experience any persistent, severe, or unusual reactions.
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[48] Incomplete list of affected drugs [edit] By enzyme [edit] Drugs that interact with grapefruit compounds at CYP3A4 include: benzodiazepines: triazolam (Halcion), orally administered midazolam (Versed), orally administered nitrazepam (Mogodon), diazepam (Valium), [49] clonazepam [50] [51] (Klonopin), alprazolam (Xanax) and quazepam (Doral, Dormalin) [52] ritonavir (Norvir): Inhibition of CYP3A4 prevents the metabolism of protease inhibitors such as ritonavir
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Patients taking GLP-1 agonists most commonly complain of gastrointestinal effects, 2 such as unsettled stomach, upset GI tract, variable bowel movements or trouble with elimination, abdominal discomfort, and gastroesophageal discomfort