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A Herxheimer reaction can be elicited by any therapy that is causing the destruction of endotoxin-creating organisms or causing the release of endotoxins from places they are being stored in the body, such as: Ozone IV or insufflation High dose vitamin C Antibiotics Anti-parasitics Anti-virals Antimicrobials Any oxidative therapy that boosts immunity or kills pathogens How can I support my body during a Herxheimer reaction

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The isomerization reaction of PGF 2 to PGD 2 is also catalyzed by sigma class of GST

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doi: 10.1016/j.tips.2005.09.002