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When the calcium binds to a protein called synaptotagmin, on the vesicles' surfaces, synaptotagmin teams up with other proteins to tug some of the vesicles, winch-style, closer and closer to the neuron's surface membrane until their enclosing membranes fuse with it, spilling the vesicles' contents into the surrounding environment

This is subject to passing the medical screen

Enough to notice

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Manufacturing in California alongside its Swiss headquarters