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Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 should not use these medications

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Triple agonist peptides need more controls, wider biomarker arrays, and granular batch verification for cross-lab reproducibility

This affects both hunger signals and the pleasure response to food

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In obese patients without diabetes, their use was linked to a significantly lower incidence and progression of primary open-angle glaucoma (POAG) and ocular hypertension compared to other weight-loss drugs [102]