Thats where semaglutide comes in, a medication that has been shown to be effective for weight loss when used in combination with lifestyle changes
A similar protection against steatosis has been previously noted in GCLM KO mice challenged with other liver toxicants 38 or stress-inducing diets 17,39
In a phase 1b trial, 20 weeks of cagrilintide 2.4 mg once weekly in combination with semaglutide 2.4 mg once weekly (cagrisema) resulted in up to 17.1% WL compared to 9.5% WL with semaglutide 2.4 mg plus placebo in people with obesity [88]
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Higher doses may occasionally cause a fish-like body odor due to the way L-carnitine is metabolized
Do not assume these side effects will resolve on their own